Strasbourg, Johann Prüss (1497). 17th Century Leather Binding [28.5 x 20 cm] with Gilded Element at the Center of the Front and Back Covers; With title on Bened Spine: Tractat de Herbis. In-folio. 360 unnumbered leaves. Text divided into two columns/page (4 columns/page in the case of the register). With over 1050 in-text Woodcuts [approx. 11 x 7 cm] and 3 full-page Woodcuts. With some decorative margin notes (images of human heads or hands pointing towards a certain paragraph). This very rare Incunable was first published by Jacob Meydenbach in Mainz, in the year 1491 (Hain 8940. GW 13549). Hortus Sanitatis is a very early natural history encyclopedia, a comprehensive work which explores various species in the natural world, detailing their medicinal uses and methods of preparation. Dif.